targeting stem cells could be a long term weapon to battle obesity

Image Courtesy Sydney Morning Herald

Pills and diets and workouts – oh my.  Go to the health section at the grocery store and look around.  Notice how obsessed we are with weight loss in this society.  It may be a good thing, seeing as how obesity is a leading cause of preventable death worldwide, but that’s beside the point.

As obesity is linked to such ailments as diabetes, cardiovascular disease, cancer, sleep apnea and osteoarthritis, it should be no surprise that there’s a similar obsession with curbing obesity in the field of medical research.  Obviously the best approach to combat obesity is a healthy diet and exercise, but researchers at the UT Health Science Center at Houston are beginning to develop a novel approach to control bulging waistlines.  The lab of Dr. Mikhail Kolonin, in a study published in Cell Stem Cell, reports on a technique that can be used to target the stem cells that make fat in the adult. Continue reading

sitagliptin: duct tape for diabetes treatment

Any of you remember the days when duct tape was actually used to repair and seal ductwork?  Of course you don’t.  It’s one of the greatest examples ever of a product being utilized for purposes outside their original intent.  Wallets, bags, prom dresses, even fixing up an airplane wing.  If the inventors of the adhesive wonder had had any idea….

Wouldn’t it be awesome if disease treatments worked like that too?  I mean, some do.  The drug we know far and wide as Rogaine was originally marketed as a treatment for high blood pressure.  Its curious side effects are now, of course, the hope of millions.

On a similar note of interest in current news, Dr. Paul Ernsberger and company of the Case Western Reserve University Department of Nutrition have published a research article in journal of Experimental Biology and Medicine in which they examined the potential for a diabetes drug, sitagliptin, to prevent the onset of type 2 diabetes in the first place. Continue reading